Revenue and Taxation. Financial Services. Office of Information Technology. Procurement Services. More than half of the people with cancer receive some form of radiotherapy, which is increasingly used in combination with chemotherapy or immunotherapy to increase progression-free survival. Today's radiotherapy systems must use bigger targets for radiation than is necessary due to uncertainty about the exact location of disease or to account for movement during treatment.
The hope is that the currently experimental BgRT technique will spare healthy bystander cells thanks to more precise imaging and targeting. City of Hope's An Liu , Ph. The U. It is expected to be ready for City of Hope's patients in the first quarter of As one example, prostate-specific membrane antigen tracers are currently being commercialized for prostate cancer detection and staging.
Research efforts are underway to study how these new tracers can be used in offline and real-time BgRT paradigms. Real-time BgRT will enable delivery of a tracked radiation dose to multiple tumors in the same session by making the tumors themselves continuously signal their location. This real-time information can serve to spare healthy tissues by potentially allowing physicians to reduce margins added to compensate for tumor motion in conventional radiotherapy, thereby reducing toxicity without compromising the dose to the targets.
A conventional image-guided approach can require the use of implanted fiducial markers or surrounding anatomy to serve as surrogates for motion management.
Such conventional approaches rely on a motion management process whose complexity varies by anatomic region. This remains the largest barrier to multitumor treatment. In addition to the potential margin reduction and toxicity savings that a tracked dose delivery can achieve for a single tumor, the potential to treat multiple tumors throughout the body in the same session opens the door to combination therapy paradigms that have yet to be accessed by those in the metastatic patient population.
The previously described randomized trial results suggest that external-beam radiation therapy can be used in a synergistic fashion to enhance the abilities of immunotherapies and other advanced systemic treatments in attacking cancer. If these hypotheses continue to be supported by mounting clinical evidence, BgRT may become an important tool in a combination therapy approach to metastatic cancer.
References 1. The display payload immediately follows the capsule header. The firmware update display capsule describes a graphic that must be rendered during the duration of a firmware update. The graphic is initially rendered and display by Windows and handed off to the firmware as part of the same UpdateCapsule call containing the update payload s to the firmware.
If the firmware resets the system or the video device, the firmware must redisplay the bitmap provided in the display capsule. If physical memory is not persisted across the reset, the firmware may have to save the bitmap to persistent storage to redisplay the bitmap after the reset. The details on how to save and restore the bitmap across a reset are implementation specific and are not discussed in this paper. While the two tables are similar, there are a couple of notable differences.
User experience for UEFI firmware updates. Feedback will be sent to Microsoft: By pressing the submit button, your feedback will be used to improve Microsoft products and services. Privacy policy. Skip to main content. This browser is no longer supported.
Download Microsoft Edge More info. Contents Exit focus mode. OEM logo The OEM logo in the firmware update boot screen must be the same logo which is displayed during the normal boot process. Create the logo The logo you add presents customers with their first visual encounter with their new PCs running Windows, so it should be clean, crisp, and sharp on its edges as well as inside.
These design principles apply to both landscape and portrait devices. Is this page helpful? Yes No. Any additional feedback?
0コメント