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J Psychopharmacol 19 : — Wesensten NJ Effects of modafinil on cognitive performance and alertness during sleep deprivation. Curr Pharm Des 12 : — Maintaining alertness and performance during sleep deprivation: modafinil versus caffeine. For the treatment of ADHD, these medications have not been directly compared in clinical studies. However, according to an analysis of clinical studies, Vyvanse appears to be more effective than Provigil for treating ADHD in adults. These medications have also not been directly compared in clinical studies looking at decreasing daytime sleepiness in people with narcolepsy or other disorders.
Provigil and Vyvanse are brand-name drugs. Provigil is also available in a generic form called modafinil, but Vyvanse is not available as a generic. Provigil costs more than Vyvanse. However, the generic version of Provigil costs less than Vyvanse. The actual amount you pay will depend on your health insurance plan.
The drug works in the brain to increase amounts of certain chemical messengers such as dopamine. It also seems to affect the messenger glutamate in certain areas of the brain. These actions may result in stimulation of brain activities, which could make you feel less tired. Provigil begins to work within 30 to 60 minutes of when you take it. If you take it with food, the drug might take slightly longer to start working.
Some research in animals has shown negative effects to a fetus when the mother takes this drug. Slowed growth of the fetus and spontaneous abortion have occurred in women who took Provigil. This medication should only be used during pregnancy if the benefit justifies the potential risk. If you do take Provigil while pregnant, you can sign up for a registry that will help gather information about your experience. Pregnancy exposure registries help healthcare professionals learn more about how certain drugs affect women and their pregnancies.
To sign up, call You may need to decide whether to stop breastfeeding or stop taking this medication. For most people, it usually takes 30 to 60 minutes to start working. If you take Provigil with food, it might take slightly longer. Modalert is another name for Provigil. This form of Provigil is sold in countries outside of North America. For most people who take Provigil as prescribed by their doctor, it continues to work even when taken for long periods of time.
They may need to increase your dosage or consider a different medication. If you think you or your child has taken too much of this drug, call your doctor or seek guidance from the American Association of Poison Control Centers at or through their online tool.
But if your symptoms are severe, call or go to the nearest emergency room right away. When Provigil is dispensed from the pharmacy, the pharmacist will add an expiration date to the label on the bottle. This date is typically one year from the date the medication was dispensed. However, an FDA study showed that many medications may still be good beyond the expiration date listed on the bottle.
How long a medication remains good can depend on many factors, including how and where the medication is stored. Provigil should be stored at room temperature. If you have unused medication that has gone past the expiration date, talk to your pharmacist about whether you might still be able to use it.
Before taking Provigil, talk with your doctor about your health history. Provigil may not be right for you if you have certain medical conditions. These include:. Provigil is a stimulant with effects dissimilar compared to other central nervous stimulants such as amphetamine or methylphenidate.
Provigil does not have alpha-adrenergic effects, but the alpha-adrenergic antagonist prazosin can decrease the wakefulness effects of Provigil. Provigil dopamine reuptake does not have dopamine receptor agonist activity. Dopamine antagonists do not block wakefulness from Provigil.
Animal studies show that Provigil increases glutaminergic activity in the thalamus and hippocampus. Provigil is readily absorbed when taken orally and reaches peak plasma concentration within 2 to 4 hours. Peak levels may be delayed by about an hour when the drug is taken with food. Provigil is primarily eliminated via the liver. Provigil induces cytochrome P 3A4 and induces its own metabolism through this route. Provigil is contraindicated in people who have had a hypersensitivity reaction to Provigil or Nuvigil armodafinil in the past.
Provigil is a Schedule IV controlled substance. Studies show that Provigil has the potential to cause euphoric effects and feelings consistent with other stimulants, including methylphenidate. People with a history of alcohol or drug abuse may have a higher risk of abusing Provigil. Disclaimer : MedicalNewsToday has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional.
You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
What is hypopnea and how does it differ from sleep apnea? What are the risk factors of hypopnea, how may it be prevented, and what are the…. Ritalin methylphenidate is a stimulant medication for the treatment of ADHD and narcolepsy. Ritalin can cause side effects and has the potential for…. Some research links amphetamine use to…. A person with sleep apnea will repeatedly stop breathing when asleep then gasp when breathing returns. It has links with various health conditions….
Narcolepsy is a chronic sleep disorder wherein the brain cannot regulate the body's sleep-wake cycles. A person may fall asleep unexpectedly. Provigil modafinil. Nuvigil Provigil vs. Provigil generic. Provigil side effects. Provigil uses. Provigil dosage. How to take Provigil. How does Provigil appear on a drug test?
Provigil interactions. Provigil and alcohol. Provigil abuse. Select personalised content. Create a personalised content profile. Measure ad performance. Select basic ads. Create a personalised ads profile. Select personalised ads.
Apply market research to generate audience insights. Measure content performance. Develop and improve products. List of Partners vendors. Modafinil, also known by its brand name Provigil, is a central nervous stimulant that has been approved by the U. Food and Drug Administration to treat daytime sleepiness in individuals who have conditions that include narcolepsy, shift work disorder, and sleepiness caused by medical conditions such as sleep apnea.
However, it is also sometimes misused without a prescription. Plenty of people misuse cognitive-enhancing or psychostimulant drugs in a nonprescription capacity in order to increase productivity, combat fatigue, and help with intellectual challenges.
However, it is not uncommon for other groups of people to misuse these drugs as well. For example, 8. Modafinil is supposed to be less addictive than other psychostimulants like amphetamine, but some evidence suggests that dependence and abuse are possible. Modafinil is sometimes called a "wakefulness-promoting agent.
Modafinil affects the hypothalamus, hippocampus, and amygdala which are parts of the brain. Modafinil is a tablet taken by mouth usually once-a-day. However, shift workers who take the drug to promote wakefulness take the drug before their shifts begin. Modafinil is used to treat problems with sleep, arousal, and wakefulness. Some conditions treated with modafinil include the following:. Modafinil's most common adverse effects include the following:.
Other adverse effects include the following:.
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